Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044110 | 0.67 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1TSHRNPSR1 | |
| SCHEMBL964566 | 0.64 | CNR1 (0.42) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL6891227 | 0.64 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1TSHRNPSR1 | |
| SCHEMBL4082300 | 0.62 | CNR2 (0.45) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL967095 | 0.62 | CNR2 (0.45) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL966037 | 0.62 | CNR2 (0.45) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL967097 | 0.62 | CNR2 (0.45) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL963095 | 0.62 | CNR2 (0.45) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL5858380 | 0.60 | MEN1 (0.57) | KMT2AMEN1HSD11B1ALDH1A1TSHR | |
| SCHEMBL1056100 | 0.59 | KMT2A (0.39) | KMT2AALDH1A1CNR2NPSR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024349-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Abbott Laboratories (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007140439-A2 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |