Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F9 | P00740 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | F12 | P00748 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141818 | 0.84 | F2 (0.33) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL954492 | 0.84 | CHRNB2 (0.37) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL3272707 | 0.81 | SLC6A1 (0.36) | — | |
| SCHEMBL15542301 | 0.81 | SLC6A1 (0.36) | — | |
| SCHEMBL4383814 | 0.81 | SLC6A1 (0.36) | — | |
| SCHEMBL2922483 | 0.80 | CHRNB2 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL23827563 | 0.78 | KDM4E (0.37) | — | |
| SCHEMBL17276241 | 0.78 | SLC6A1 (0.31) | — | |
| SCHEMBL3785744 | 0.78 | KDM4E (0.37) | — | |
| SCHEMBL30111027 | 0.78 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052200-A2 | HUMAN ADAM-10 INHIBITORS | SYMPHONY EVOLUTION, INC. (US) | 2009-04-23 | — | — | WO | disclosed |