Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081823 | 0.92 | TSHR (0.62) | MAPTTSHRHSD17B10GAAMAOB | |
| SCHEMBL18868426 | 0.90 | GAA (0.59) | MAPTTSHRHSD17B10GAAPSIP1 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.85 | TSHR (0.68) | MAPTTSHRHSD17B10PSIP1KEAP1 | |
| Benzylsulfonylbenzene SCHEMBL1877584 | 0.83 | TSHR (0.66) | MAPTTSHRHSD17B10PSIP1KEAP1 | |
| SCHEMBL11331449 | 0.82 | CA2 (0.65) | MAPTTSHRGAACA1CA2 | |
| SCHEMBL3381366 | 0.81 | GAA (0.55) | MAPTTSHRGAAPSIP1HTR6 | |
| SCHEMBL7082360 | 0.81 | CYP3A4 (0.47) | MAPTTSHRHSD17B10GAAPSIP1 | |
| SCHEMBL6509990 | 0.81 | MAOB (0.57) | GAAMAOBMAOAPSIP1KEAP1 | |
| SCHEMBL30963220 | 0.81 | MEN1 (0.60) | TSHRGAAPSIP1HTR6CA1 | |
| SCHEMBL11114440 | 0.80 | MAPT (0.61) | MAPTTSHRHSD17B10PSIP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203585-A1 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ARRAY BIOPHARMA, INC. | 2009-08-13 | — | — | US | disclosed |
| WO-2007130743-A2 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ARRAY BIOPHARMA, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-7294616-B2 | Capreomycin derivatives and their use as antibacterials | ARRAY BIOPHARMA, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| WO-2006052499-A1 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ARRAY BIOPHARMA, INC. (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20060094644-A1 | Capreomycin derivatives and their use as antibacterials | ARRAY BIOPHARMA, INC. | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203585-A1 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | CAPRIN1, NISCH, RPIA | MAPT 2831/4885TSHR 3596/4885HSD17B10 3074/4885 |
| US-20060094644-A1 | Capreomycin derivatives and their use as antibacterials | SPOUT1, CAPRIN1, FBL | MAPT 834/4885TSHR 3260/4885HSD17B10 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.