⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34847 | 0.84 | — | — | |
| SCHEMBL13654861 | 0.78 | — | — | |
| SCHEMBL17520435 | 0.78 | — | — | |
| SCHEMBL17520439 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL17493902 | 0.77 | — | — | |
| SCHEMBL18074416 | 0.74 | — | — | |
| SCHEMBL4655460 | 0.73 | — | — | |
| SCHEMBL4054528 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL20299016 | 0.71 | — | — | |
| SCHEMBL2028609 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057140-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008023159-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | WO | disclosed |