Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.73 |
| ▸ | USP2 | O75604 | 6/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.72 |
| ▸ | MMP2 | P08253 | 1/20 | 0.72 |
| ▸ | MMP3 | P08254 | 1/20 | 0.72 |
| ▸ | MMP7 | P09237 | 1/20 | 0.72 |
| ▸ | MMP8 | P22894 | 1/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | MMP13 | P45452 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 7/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005369 | 1.00 | TDP1 (0.73) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL21014939 | 1.00 | TDP1 (0.73) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL40930 | 1.00 | TDP1 (0.73) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL4082642 | 1.00 | TDP1 (0.73) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL1176275 | 1.00 | TDP1 (0.73) | TDP1USP2HSD17B10HIF1ATSHR | |
| Water SCHEMBL1649970 | 0.99 | MMP2 (0.74) | TDP1USP2HSD17B10HIF1ATSHR | |
| Water SCHEMBL537059 | 0.97 | MMP2 (0.72) | TDP1USP2HSD17B10HIF1ATSHR | |
| Alcohol SCHEMBL14973542 | 0.94 | KDM4E (0.72) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL18610140 | 0.92 | TDP1 (0.65) | TDP1USP2HSD17B10HIF1ATSHR | |
| SCHEMBL21793722 | 0.85 | TDP1 (1.00) | TDP1USP2HSD17B10HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181330-B2 | COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS | STATENS SERUMINSTITUT (DK) | 2016-08-31 | — | — | EP | disclosed |
| US-20090035229-A1 | PHARMACEUTICAL COMPOSITION FOR IMPROVING ORAL HYGIENE AND METHODS THEREOF | EIREW GARY H | 2009-02-05 | — | — | US | disclosed |