⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1712802 | 0.89 | NAPRT (0.52) | — | |
| SCHEMBL29793056 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL1368828 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL28129237 | 0.76 | CYP2A6 (0.60) | — | |
| SCHEMBL84647 | 0.75 | — | — | |
| SCHEMBL115502 | 0.75 | — | — | |
| SCHEMBL14833557 | 0.75 | — | — | |
| SCHEMBL22113986 | 0.75 | — | — | |
| SCHEMBL238813 | 0.75 | — | — | |
| SCHEMBL30212452 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076479-B2 | useful as cyclin-dependent kinase inhibitor compounds; minimizes the need for chromatographic purification of intermediates, and utilizes fewer changes of solvent systems | SCHERING CORPORATION (US) | 2011-12-13 | — | — | US | claimed |
| EP-2057166-A2 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF (3-ALKYL-5-PIPERIDIN-1-YL-3,3A-DIHYDRO- PYRAZOLOÝ1,5-A¨PYRIMIDIN-7-YL)-AMINO DERIVATIVES AND INTERMEDIATES | SCHERING CORPORATION (US) | 2009-05-13 | — | — | EP | claimed |
| WO-2008027220-A2 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF (3-ALKYL-5-PIPERIDIN-1-YL-3, 3A-DIHYDROPYRAZOL0 [1, 5-A] PYRIMIDIN-7-YL) -AMINO DERIVATIVES | SCHERING CORPORATION (US) | 2008-03-06 | — | — | WO | claimed |
| US-20080058518-A1 | Process and intermediates for the synthesis of (3-alkyl-5-piperidin-1-yl-3,3a-dihydro-pyrazolo[1,5-a]pyrimidin-7-yl)-amino derivatives and intermediates | MERCK SHARP & DOHME LLC | 2008-03-06 | — | — | US | claimed |
| EP-3010596-A1 | COMPOSITION COMPRISING AN OXIDISING AGENT, A SPECIFIC AMINOPYRIDINE OXIDATION BASE AND FATS, AND DYEING METHOD USING SAID COMPOSITION AND A CATALYST | L'OREAL (FR) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014202921-A1 | COMPOSITION COMPRISING AN OXIDISING AGENT, A SPECIFIC AMINOPYRIDINE OXIDATION BASE AND FATS, AND DYEING METHOD USING SAID COMPOSITION AND A CATALYST | L'OREAL (FR) | 2014-12-24 | — | — | WO | disclosed |
| US-20130072527-A1 | METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS | ACORDA THERAPEUTICS, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072527-A1 | METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS | ACORDA THERAPEUTICS, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2010030755-A1 | METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS | ACORDA THERAPEUTICS, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| US-20100061935-A1 | METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS | ACORDA THERAPEUTICS, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100061935-A1 | METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS | ACORDA THERAPEUTICS, INC. (US) | 2010-03-11 | — | — | US | disclosed |