Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489362 | 0.81 | GABRA1 (0.36) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| Hydrochloric Acid SCHEMBL4083622 | 0.79 | GABRA1 (0.35) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| Hydrochloric Acid SCHEMBL4066285 | 0.79 | GABRA1 (0.35) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| Hydrochloric Acid SCHEMBL8152646 | 0.78 | CYP1A2 (0.31) | CA1CA2CYP1A2HTR2C | |
| Hydrochloric Acid SCHEMBL28327569 | 0.78 | GABRA1 (0.34) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| Hydrochloric Acid SCHEMBL27463390 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL29612270 | 0.78 | GABRA1 (0.34) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| Hydrochloric Acid SCHEMBL2529411 | 0.78 | GABRA1 (0.34) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| SCHEMBL6261653 | 0.77 | GABRA1 (0.36) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| SCHEMBL28056689 | 0.77 | GABRA1 (0.36) | GABRA1GABRG2GABRB3LMNAGABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845546-A | Substituted metallocene catalysts | 埃克森美孚化学专利公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110845546-A | Substituted metallocene catalysts | 埃克森美孚化学专利公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-103443171-B | Polyethylene film | 伊奎斯塔化学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| WO-2009104782-A1 | ETHYLENE HOMOPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104785-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104783-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |