SCHEMBL4082758

SCHEMBL4082758

Brc1cccc([C](c2cccc(Br)c2)c2cccc(Br)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1S P09871 1/20 0.60
PARP1 P09874 1/20 0.60
ALDH1A1 P00352 3/20 0.52
TP53 P04637 1/20 0.52
HPGD P15428 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
MAPK1 P28482 1/20 0.46
GLA P06280 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
NPC1 O15118 1/20 0.43
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GAA P10253 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513249 0.80 PARP1 (0.63) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL8865210 0.79 C1S (0.56) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL6670439 0.79 PARP1 (0.68) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL241785 0.79 PARP1 (0.68) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL30153175 0.79 PARP1 (0.68) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL749086 0.79 C1S (0.56) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL8681033 0.77 PARP1 (0.65) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL180430 0.77 PARP1 (0.65) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL20894576 0.77 PARP1 (0.59) C1SPARP1ALDH1A1TP53HPGD
SCHEMBL9586439 0.77 C1S (0.54) C1SPARP1ALDH1A1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-6900280-B2 Acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-31 US disclosed
US-20040072978-A1 Compositions of acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. 2004-04-15 US disclosed
EP-1392736-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-6576684-B1 Ammonium, phosphonium or sulfonium containing oligomers or polymers; controlled molecular weight, low polydispersity and a vinyl or dienyl end group; polymeric precursors and addi-tives CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-10 US disclosed
US-6489374-B1 ORGANONITROGEN COMPOUNDS THAT YIELD AMINES, IMINES OR AMIDINES WHEN EXPOSED TO VISIBLE OR ULTRAVIOLET RADIATION; POLYMERIZATION CATALYSTS USED IN ONE-POT SYSTEMS HAVING STORAGE STABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 US disclosed
EP-1105368-B1 PHOTOACTIVATABLE BASES CONTAINING NITROGEN CIBA SC HOLDING AG (CH) 2002-10-30 EP disclosed
WO-2002079271-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-1105368-A1 PHOTOACTIVATABLE BASES CONTAINING NITROGEN Ciba SC Holding AG (CH) 2001-06-13 EP disclosed
WO-2000010964-A1 PHOTOACTIVATABLE BASES CONTAINING NITROGEN CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-02 WO disclosed