Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203800 | 0.90 | ATM (0.55) | ATMALDH1A1ALDH1A3TSHRTRIM24 | |
| SCHEMBL13742990 | 0.81 | KCNJ1 (0.42) | ATMALDH1A1ALDH1A3TSHRKCNJ1 | |
| SCHEMBL4100764 | 0.75 | ALDH1A1 (0.52) | ATMALDH1A1ALDH1A3TSHRTRIM24 | |
| SCHEMBL4082754 | 0.75 | ALDH1A1 (0.52) | ATMALDH1A1ALDH1A3TSHRTRIM24 | |
| SCHEMBL4211677 | 0.74 | KCNN4 (0.66) | ALDH1A1TSHRHPGDKCNN4MAPT | |
| SCHEMBL4201299 | 0.72 | ALDH1A1 (0.52) | ATMALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL4205532 | 0.72 | ATM (0.45) | ATMALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL4202229 | 0.72 | ATM (0.51) | ATMALDH1A1ALDH1A3TSHRTRIM24 | |
| SCHEMBL15786417 | 0.72 | KMT2A (0.55) | ATMALDH1A1TSHRHPGDKCNN4 | |
| SCHEMBL4082746 | 0.72 | ALDH1A1 (0.59) | ATMALDH1A1ALDH1A3TSHRTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090131498-A1 | Enantioselective Synthesis of Merrilactone and Its Analogs | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-05-21 | — | — | US | disclosed |
| EP-2019094-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131498-A1 | Enantioselective Synthesis of Merrilactone and Its Analogs | PMP22, CYP51A1, NTRK1 | ATM 3950/4885ALDH1A1 934/4885ALDH1A3 403/4885 |
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | CLIC4, NR3C2, MAN2B1 | ATM 3029/4885ALDH1A1 159/4885ALDH1A3 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.