Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082754 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL4083040 | 0.75 | ATM (0.54) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL4082710 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL4082746 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL1237357 | 0.69 | ALDH1A1 (0.52) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL758550 | 0.69 | PSEN1 (0.57) | ALDH1A1ALDH1A3 | |
| SCHEMBL29940580 | 0.69 | PSEN1 (0.57) | ALDH1A1ALDH1A3 | |
| SCHEMBL1049476 | 0.69 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL23043 | 0.68 | ALDH1A1 (0.70) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 | |
| SCHEMBL29956457 | 0.68 | ALDH1A1 (0.70) | ALDH1A1ALDH1A3TSHRHPGDTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2019094-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | CLIC4, NR3C2, MAN2B1 | ALDH1A1 159/4885ALDH1A3 98/4885TSHR 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.