Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35947 | 0.97 | — | — | |
| SCHEMBL9819526 | 0.97 | — | — | |
| SCHEMBL6667882 | 0.97 | — | — | |
| Water SCHEMBL4330053 | 0.94 | LMNA (0.47) | LMNAALDH1A1MAPTSLC22A16THRB | |
| Hydrochloric Acid SCHEMBL35525 | 0.94 | MAPT (0.50) | LMNAALDH1A1MAPTSLC22A16THRB | |
| Bromide SCHEMBL8408095 | 0.94 | LMNA (0.47) | LMNAALDH1A1MAPTSLC22A16THRB | |
| Hydrochloric Acid SCHEMBL9819532 | 0.94 | MAPT (0.50) | LMNAALDH1A1MAPTSLC22A16THRB | |
| Ammonia Solution, Strong SCHEMBL27633517 | 0.91 | MAPT (0.48) | LMNAALDH1A1MAPTSLC22A16THRB | |
| Ethylene Glycol SCHEMBL3142993 | 0.88 | MAPT (0.46) | LMNAALDH1A1MAPTSLC22A16THRB | |
| SCHEMBL28282530 | 0.88 | LMNA (0.42) | LMNAALDH1A1MAPTSLC22A16THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10449483-B2 | Gas sweetening solvents containing quaternary ammonium salts | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-22 | — | — | US | claimed |
| US-20160206992-A1 | GAS SWEETENING SOLVENTS CONTAINING QUATERNARY AMMONIUM SALTS | DOW GLOBAL TECHNOLOGIES LLC | 2016-07-21 | — | — | US | claimed |
| EP-3038736-A1 | GAS SWEETENING SOLVENTS CONTAINING QUATERNARY AMMONIUM SALTS | Dow Global Technologies LLC (US) | 2016-07-06 | — | — | EP | claimed |
| EP-1086072-B1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | UNIV MICHIGAN STATE (US) | 2006-10-18 | — | — | EP | claimed |
| EP-1086072-A4 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | UNIV MICHIGAN STATE (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1086072-A1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2001-03-28 | — | — | EP | claimed |
| US-6084131-A | Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-07-04 | — | — | US | claimed |
| WO-1999062863-A1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 1999-12-09 | — | — | WO | claimed |
| US-10449483-B2 | Gas sweetening solvents containing quaternary ammonium salts | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-22 | — | — | US | disclosed |
| US-20160206992-A1 | GAS SWEETENING SOLVENTS CONTAINING QUATERNARY AMMONIUM SALTS | DOW GLOBAL TECHNOLOGIES LLC | 2016-07-21 | — | — | US | disclosed |
| EP-3038736-A1 | GAS SWEETENING SOLVENTS CONTAINING QUATERNARY AMMONIUM SALTS | Dow Global Technologies LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC | 2006-10-26 | — | — | US | disclosed |
| EP-1086072-B1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | UNIV MICHIGAN STATE (US) | 2006-10-18 | — | — | EP | disclosed |
| EP-1086072-A1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2001-03-28 | — | — | EP | disclosed |
| US-6084131-A | Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-07-04 | — | — | US | disclosed |
| WO-1999062863-A1 | PROCESS FOR THE PREPARATION OF PROTECTED DIHYDROXYPROPYL TRIALKYLAMMONIUM SALTS AND DERIVATIVES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0257619-B1 | PROCESS FOR PREPARING 3-HALOGENO-2-HYDROXYPROPYLTRIMETHYLAMMONIUM HALIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |
| US-4814506-A | Process for preparing 3 halogeno-2-hydroxypropyltrimethylammonium halide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-03-21 | — | — | US | disclosed |
| EP-0257619-A2 | Process for preparing 3-halogeno-2-hydroxypropyltrimethylammonium halide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | ANXA6, STING1, POLRMT | CHRM1 3636/4885CHRM3 3171/4885LMNA 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.