Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682972 | 1.00 | FDFT1 (0.46) | FDFT1CHRM4PRMT5BCHEALOX5 | |
| SCHEMBL4083380 | 1.00 | FDFT1 (0.46) | FDFT1CHRM4PRMT5BCHEALOX5 | |
| SCHEMBL6622776 | 0.87 | FDFT1 (0.44) | FDFT1CHRM4BCHEALOX5NPC1 | |
| SCHEMBL8218213 | 0.84 | FDFT1 (0.47) | FDFT1CHRM4BCHEALOX5NPC1 | |
| SCHEMBL1941467 | 0.84 | FDFT1 (0.47) | FDFT1CHRM4BCHEALOX5NPC1 | |
| SCHEMBL8218218 | 0.84 | FDFT1 (0.47) | FDFT1CHRM4BCHEALOX5NPC1 | |
| SCHEMBL4602100 | 0.76 | HRH3 (0.49) | FDFT1CHRM4PRMT5BCHENPC1 | |
| SCHEMBL4602103 | 0.76 | HRH3 (0.49) | FDFT1CHRM4PRMT5BCHENPC1 | |
| SCHEMBL2683449 | 0.73 | CHRM4 (0.42) | CHRM4BCHEALOX5NPC1RAB9A | |
| SCHEMBL2338156 | 0.73 | CHRM4 (0.42) | CHRM4BCHEALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |