Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941467 | 1.00 | FDFT1 (0.47) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL8218218 | 1.00 | FDFT1 (0.47) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL6622776 | 0.85 | FDFT1 (0.44) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL2682972 | 0.84 | FDFT1 (0.46) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL4083377 | 0.84 | FDFT1 (0.46) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL4083380 | 0.84 | FDFT1 (0.46) | FDFT1CHRM4ALOX5ACACBBCHE | |
| SCHEMBL8220896 | 0.79 | NPC1 (0.55) | FDFT1NPC1RAB9AS1PR5MAPK1 | |
| SCHEMBL8220899 | 0.79 | NPC1 (0.55) | FDFT1NPC1RAB9AS1PR5MAPK1 | |
| SCHEMBL4602100 | 0.78 | HRH3 (0.49) | FDFT1CHRM4BCHENPC1RAB9A | |
| SCHEMBL4602103 | 0.78 | HRH3 (0.49) | FDFT1CHRM4BCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063173-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PIPERIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-26 | — | — | WO | disclosed |