SCHEMBL408354

SCHEMBL408354

F[C](F)C(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8215520 0.76
SCHEMBL8215521 0.76
SCHEMBL2118974 0.76
SCHEMBL303510 0.73
SCHEMBL4066794 0.73
SCHEMBL4858511 0.73
SCHEMBL3906946 0.73
SCHEMBL3908235 0.73
SCHEMBL404184 0.70 LMNA (0.30)
SCHEMBL2471422 0.70 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438695-B Synthetic method of perfluorocyclobutyl polyarylether containing heteronaphthalene biphenyl structure 大连理工大学 2021-05-11 CN claimed
CN-109456435-B Synthetic method of perfluorocyclobutyl polyarylether containing heteronaphthalene biphenyl structure 大连理工大学 2021-05-11 CN claimed
CN-107445795-B Synthesis method of 2-bromo-1, 1, 2, 2-tetrafluoroethyl substituted aryl building block 遵义医科大学 2020-09-18 CN claimed
CN-100522903-C Polyhalide alkaryl compound BAYER AG (DE) 2009-08-05 CN claimed
CN-101296954-A Process for the manufacture of fluoroelastomers having bromine or iodine atom cure sites DUPONT PERFORMANCE ELASTOMERS (US) 2008-10-29 CN claimed
CN-1498881-A Polyhalide alkaryl compound 2004-05-26 CN claimed
US-20040092762-A1 Polyhaloalkylaryls LANXESS DEUTSCHLAND GMBH (DE) 2004-05-13 US claimed
EP-1418169-A2 Polyhalogenoalkylaryl compounds Bayer Chemicals AG (DE) 2004-05-12 EP claimed
US-5756522-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-26 US claimed
CN-1165818-A Triazole derivatives and uses thereof SUMITOMO CHEMICAL CO (JP) 1997-11-26 CN claimed
EP-0780381-A1 Triazole derivatives and uses thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-06-25 EP claimed
EP-4375286-A1 OXASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shujing Biopharma Co., Ltd (CN) 2024-05-29 EP disclosed
US-20240150312-A1 PYRAZINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-09 US disclosed
US-11905271-B2 Pyrazine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-20 US disclosed
WO-2024032530-A1 AROMATIC HETEROCYCLIC CYCLOHEXYL AMINOALKYL PIPERIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF 江苏恩华药业股份有限公司 2024-02-15 WO disclosed
EP-0535980-A1 2-Pyridone derivatives, a process for their preparation and their use as fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-07 EP disclosed
EP-0520824-A1 1-pyridylimidazole derivatives and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-12-30 EP disclosed
EP-0490569-A1 N-aryl-3-aryl-4-substitued-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamides and methods of their production ROHM AND HAAS COMPANY (US) 1992-06-17 EP disclosed
US-5109014-A Useful as insecticide or pesticide DOW AGROSCIENCES LLC, A DELAWARE LIMITED LIABILITY COMPANY 1992-04-28 US disclosed
EP-0466408-A1 N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production ROHM AND HAAS COMPANY (US) 1992-01-15 EP disclosed