Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4078444 | 0.99 | PIK3CG (0.38) | PIK3CGABL1KDM4ELMNAPOLB | |
| Hydrochloric Acid SCHEMBL4075479 | 0.79 | VCP (0.38) | PIK3CGABL1KDM4ELMNAVCP | |
| SCHEMBL3175801 | 0.72 | VCP (0.58) | KDM4ELMNAVCP | |
| SCHEMBL3166410 | 0.71 | CYP1A1 (0.51) | ABL1KDM4EVCP | |
| SCHEMBL4087254 | 0.70 | VCP (0.35) | ABL1KDM4ELMNAPOLBVCP | |
| SCHEMBL4082457 | 0.70 | VCP (0.35) | PIK3CGKDM4ELMNATRPV4VCP | |
| SCHEMBL4077729 | 0.70 | MAPT (0.59) | KDM4ELMNA | |
| SCHEMBL3527848 | 0.70 | SIRT5 (0.48) | ABL1VCP | |
| SCHEMBL4078682 | 0.69 | MEN1 (0.52) | ABL1VCP | |
| SCHEMBL4394378 | 0.68 | MAPT (0.44) | LMNAVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |