SCHEMBL4083705

SCHEMBL4083705

[c]1csc2cc3cc4ccccc4cc3cc12

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
AR P10275 1/20 0.30
MAPT P10636 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
GFER P55789 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161023 0.96 KDM4E (0.32) ALDH1A1KDM4ENPC1ARMAPT
SCHEMBL510351 0.69 ALDH1A1 (0.42) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL15714 0.69
SCHEMBL510183 0.69 ALDH1A1 (0.42) ALDH1A1CYP3A4ALOX15CASP1CASP7
Benz(B)Anthracene SCHEMBL3474922 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7
Benz(B)Anthracene SCHEMBL17849077 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL22634171 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7
Benz(B)Anthracene SCHEMBL22352910 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL25181 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7
Benz(B)Anthracene SCHEMBL7947 0.66 ALDH1A1 (0.61) ALDH1A1CYP3A4ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5352196-B2 2013-11-27 JP disclosed
JP-2009141338-A ORGANIC TRANSISTOR MITSUI CHEMICALS INC 2009-06-25 JP disclosed