Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833208 | 0.84 | TSHR (0.51) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11831804 | 0.81 | SIGMAR1 (0.49) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14427566 | 0.80 | ALDH1A1 (0.52) | SIGMAR1TSHRALDH1A1KMT2ANPSR1 | |
| SCHEMBL27515197 | 0.80 | SIGMAR1 (0.62) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11830078 | 0.80 | SIGMAR1 (0.54) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11830841 | 0.78 | SIGMAR1 (0.52) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11830823 | 0.78 | SIGMAR1 (0.52) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11839540 | 0.78 | TSHR (0.53) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3955369 | 0.77 | KDM4E (0.47) | SIGMAR1L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL11827571 | 0.76 | NPC1 (0.50) | SIGMAR1TSHRL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | disclosed |