Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28815090 | 0.96 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Bromide SCHEMBL27932994 | 0.96 | HTR2A (0.31) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Fluoride Ion SCHEMBL29025907 | 0.96 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL8584712 | 0.80 | TACR1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL8040550 | 0.79 | GSTP1 (0.37) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1539598 | 0.78 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL8084823 | 0.77 | CNR1 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7937385 | 0.76 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL4089940 | 0.76 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL1539731 | 0.76 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184847-A | Improved solution polymerization method | 万华化学集团股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114316100-B | Boron trifluoride modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 岳阳兴长石化股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114163552-B | Modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 岳阳兴长石化股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-115141298-A | Polyolefin resin and process for producing the same | DL化学株式会社 | 2022-10-04 | — | — | CN | disclosed |
| CN-111454389-B | Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin | DL化学株式会社 | 2022-07-15 | — | — | CN | disclosed |
| CN-114316100-A | Boron trifluoride modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 湖南立为新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114163552-A | Modified silica gel and preparation method and application thereof, and supported catalyst and preparation method and application thereof | 湖南立为新材料有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111511785-A | Process for preparing functionalized ethylene and propylene copolymers | SABIC环球技术有限责任公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111511786-A | Process for preparing ethylene and propylene ionomers | SABIC环球技术有限责任公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111491956-A | Process for preparing amorphous polyolefin ionomers | SABIC环球技术有限责任公司 | 2020-08-04 | — | — | CN | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |
| CN-1386765-A | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| CN-1339040-A | Catalyst for stereoregular polymerization of 2-olefin and process for producing stereoregular-olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2002-03-06 | — | — | CN | disclosed |
| EP-1153938-A1 | CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| CN-1281871-A | Flexible resin composition and its use | MITSUI CHEMICALS INC (JP) | 2001-01-31 | — | — | CN | disclosed |
| US-5969070-A | HOMOGENEOUS COMPOSITION FORMED FROM LINEAR OR BRANCHED CHAIN C3 TO C10 MONOMERS SUCH AS PROPYLENE, 1-BUTENE, 1-PENTENE, 4-METHYL-1-PENTENE, 1-HEXENE AND MIXTURES THEREOF, COMPRISING ALTERNATING ISOTACTIC AND ATACTIC DISASTEREOSEQUENCES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0802935-A4 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | UNIV LELAND STANFORD JUNIOR (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0802935-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5594080-A | POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS | LELAND STANFORD, JR. UNIVERSITY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1995025757-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-09-28 | — | — | WO | disclosed |