Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1681583 | 1.00 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL7193279 | 0.96 | ALDH1A1 (0.33) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| Fluoride Ion SCHEMBL1130843 | 0.96 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1CFTRGOPC | |
| Hydrochloric Acid SCHEMBL6287547 | 0.88 | KMO (0.33) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6287243 | 0.87 | CYP11B1 (0.32) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31621285 | 0.86 | CYP19A1 (0.30) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6287308 | 0.85 | HTR2C (0.33) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL22572737 | 0.85 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL27182248 | 0.84 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7638510 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157047-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP Corporation North America Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035975-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. (US) | 2000-06-22 | — | — | WO | disclosed |