Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084357 | 1.00 | CARM1 (0.59) | CARM1PRMT6DRD2DRD3SIGMAR1 | |
| SCHEMBL4075309 | 0.89 | DRD2 (0.56) | DRD2DRD3SIGMAR1KCNA3 | |
| SCHEMBL4075310 | 0.89 | DRD2 (0.56) | DRD2DRD3SIGMAR1KCNA3 | |
| SCHEMBL4084261 | 0.86 | DRD2 (0.55) | DRD2DRD3KCNA3 | |
| SCHEMBL4084269 | 0.86 | DRD2 (0.55) | DRD2DRD3KCNA3 | |
| SCHEMBL4075453 | 0.84 | DRD2 (0.57) | DRD2DRD3KCNA3 | |
| SCHEMBL4075451 | 0.84 | DRD2 (0.57) | DRD2DRD3KCNA3 | |
| SCHEMBL4082968 | 0.82 | DRD2 (0.64) | DRD2DRD3 | |
| SCHEMBL4082970 | 0.82 | DRD2 (0.64) | DRD2DRD3 | |
| SCHEMBL24168947 | 0.81 | CARM1 (0.47) | CARM1PRMT6DRD3SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | disclosed |
| EP-1438302-A1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR AGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003029233-A1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR AGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |