SCHEMBL4082970

SCHEMBL4082970

CC(C)(C)OC(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)CC1

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 11/20 0.64
DRD3 P35462 8/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4082968 1.00 DRD2 (0.64) DRD2DRD3
SCHEMBL13629877 0.92 DRD2 (0.64) DRD2DRD3
SCHEMBL3845261 0.92 DRD2 (0.64) DRD2DRD3
SCHEMBL13629983 0.87 DRD2 (0.61) DRD2DRD3
SCHEMBL5269048 0.87 DRD2 (0.59) DRD2DRD3
SCHEMBL4495784 0.87 DRD2 (0.61) DRD2DRD3
SCHEMBL13629915 0.86 DRD2 (0.60) DRD2DRD3
SCHEMBL4486979 0.86 DRD2 (0.60) DRD2DRD3
SCHEMBL13629935 0.86 DRD2 (0.64) DRD2DRD3
SCHEMBL4488629 0.86 DRD2 (0.64) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438302-B1 NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS RICHTER GEDEON NYRT (HU) 2012-05-30 EP disclosed
US-7473692-B2 Sulfonamide derivatives as D3-receptor ligands RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2009-01-06 US disclosed
US-20050107397-A1 Sulfonamide derivatives as d3-receptor agonists RICHTER GEDEON VEGYESZETI GYAR RT. 2005-05-19 US disclosed
EP-1438302-A1 NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR AGONISTS RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 2004-07-21 EP disclosed
WO-2003029233-A1 NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR AGONISTS Richter Gedeon Vegyészeti Gyár Rt. (HU) 2003-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107397-A1 Sulfonamide derivatives as d3-receptor agonists SLC6A3, DRD3, GPR3 DRD2 8/4885DRD3 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.