SCHEMBL4084482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4100975	0.86	HSP90AB1 (0.43)	L3MBTL1GRM4IDO1RHEBMRGPRX4
	SCHEMBL4101361	0.85	CCR5 (0.37)	RHEBCYP2C19SMN1; SMN2
	SCHEMBL4098709	0.77	HSP90AB1 (0.44)	KDM4EALDH1A1CYP2C19SMN1; SMN2
	SCHEMBL4091000	0.76	HSP90AB1 (0.51)	KDM4ECYP2C19EGFR
	SCHEMBL29661259	0.76	PIN1 (0.46)	L3MBTL1IDO1CYP1A2CYP2C9CYP2C19
	SCHEMBL7437643	0.76	PIN1 (0.46)	L3MBTL1IDO1CYP1A2CYP2C9CYP2C19
	SCHEMBL4094713	0.75	HSP90AB1 (0.51)	KDM4ESMN1; SMN2
	SCHEMBL4089680	0.72	DPP4 (0.46)	—
	SCHEMBL4089765	0.71	IDH1 (0.39)	KDM4EALDH1A1EGFRCTSS
	SCHEMBL13765758	0.71	KDM4E (0.50)	L3MBTL1IDO1KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.