Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4078876 | 0.84 | DRD2 (0.57) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| Hydrochloric Acid SCHEMBL4078869 | 0.84 | DRD2 (0.57) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| Hydrochloric Acid SCHEMBL4075538 | 0.83 | DRD2 (0.56) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| Hydrochloric Acid SCHEMBL4075541 | 0.83 | DRD2 (0.56) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| SCHEMBL4254856 | 0.82 | DRD2 (0.56) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| Hydrochloric Acid SCHEMBL4079219 | 0.81 | DRD3 (0.49) | DRD2DRD3HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL4079221 | 0.81 | DRD3 (0.49) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL4084481 | 0.80 | DRD2 (0.58) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| SCHEMBL4075532 | 0.80 | DRD2 (0.54) | DRD2ADRA1AADRA1BDRD3ADRA1D | |
| SCHEMBL4081134 | 0.77 | DRD2 (0.59) | DRD2ADRA1AADRA1BDRD3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |