Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910528 | 0.87 | LPL (0.38) | PDK2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7141200 | 0.81 | PDK2 (0.49) | PDK2TDP2PGRMEN1APAF1 | |
| SCHEMBL15910685 | 0.81 | PDK2 (0.43) | PDK2 | |
| SCHEMBL28877331 | 0.80 | PDK2 (0.40) | PDK2 | |
| SCHEMBL18204437 | 0.80 | PDK2 (0.40) | PDK2TDP2MEN1APAF1NPC1 | |
| SCHEMBL30714711 | 0.80 | PDK2 (0.56) | PDK2TDP2MEN1APAF1NPC1 | |
| SCHEMBL29549175 | 0.80 | PDK2 (0.56) | PDK2TDP2MEN1APAF1NPC1 | |
| SCHEMBL12520490 | 0.80 | PDK2 (0.56) | PDK2TDP2MEN1APAF1NPC1 | |
| SCHEMBL15910709 | 0.79 | — | — | |
| SCHEMBL1655554 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9634255-B2 | Aromatic amine derivative and organic electroluminescence element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| EP-2006278-B2 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2016-10-12 | — | — | EP | disclosed |
| US-8993805-B2 | Benzofluorene compound and use thereof | TOSOH CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140374720-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-2762478-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | Idemitsu Kosan Co., Ltd (JP) | 2014-08-06 | — | — | EP | disclosed |
| EP-2006278-B1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-2006278-A9 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2006278-A2 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1400578-B1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | TOSOH CORP (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | PDK2 2093/4885TDP2 4500/4885PGR 775/4885 |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | SLC7A1, SLC43A1, SLC7A5 | PDK2 3352/4885TDP2 3900/4885PGR 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.