Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Paraquat. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.72 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.72 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.72 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | QDPR | P09417 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paraquat SCHEMBL21652 | 0.96 | SLC6A4 (0.77) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL4895671 | 0.96 | SLC6A4 (0.77) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL22370108 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL8331549 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| SCHEMBL14596518 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL11281521 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL21653 | 0.93 | SLC6A4 (0.72) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL8852265 | 0.90 | SLC22A2 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL30968908 | 0.90 | SLC6A4 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL599615 | 0.90 | SLC22A2 (0.68) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132649-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | claimed |
| WO-2020234422-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-11-26 | — | — | WO | claimed |
| US-8337900-B2 | Reverse-phase microcapsules for active ingredients, simplified process of manufacture thereof and combined formulation WDG-CS, ZC, EC-SC, and CX | FMC CORPORATION | 2012-12-25 | — | — | US | claimed |
| US-20090053271-A1 | Reverse-Phase Microcapsules for Actice Ingredients, Simplified Process of Manufacture Thereof and Combined Formulation Wdg- Cs,Zc, Ec-Sc, and Cx | FMC CORPORATION | 2009-02-26 | — | — | US | claimed |
| EP-2004718-A1 | REVERSE-PHASE MICROCAPSULES FOR ACTIVE INGREDIENTS, SIMPLIFIED PROCESS OF MANUFACTURE THEREOF AND COMBINED FORMULATIONS WDG-CS, ZC, EC-SC AND CX | GAT Microencapsulation AG (AT) | 2008-12-24 | — | — | EP | claimed |
| WO-2007112933-A1 | REVERSE-PHASE MICROCAPSULES FOR ACTIVE INGREDIENTS, SIMPLIFIED PROCESS OF MANUFACTURE THEREOF AND COMBINED FORMULATIONS WDG-CS, ZC, EC-SC AND CX | GAT MICROENCAPSULATION AG (AT) | 2007-10-11 | — | — | WO | claimed |
| JP-54107886-A | — | — | None | — | — | JP | disclosed |
| JP-54109086-A | — | — | None | — | — | JP | disclosed |
| WO-2024132649-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | disclosed |
| WO-2020234422-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-11-26 | — | — | WO | disclosed |
| US-8337900-B2 | Reverse-phase microcapsules for active ingredients, simplified process of manufacture thereof and combined formulation WDG-CS, ZC, EC-SC, and CX | FMC CORPORATION | 2012-12-25 | — | — | US | disclosed |
| US-7500895-B2 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2009-03-10 | — | — | US | disclosed |
| US-20090053271-A1 | Reverse-Phase Microcapsules for Actice Ingredients, Simplified Process of Manufacture Thereof and Combined Formulation Wdg- Cs,Zc, Ec-Sc, and Cx | FMC CORPORATION | 2009-02-26 | — | — | US | disclosed |
| US-6455469-B1 | SUBSTITUTED ACETANILIDE DERIVATIVE IN COMBINATION WITH OTHER HERBICIDE TO GIVE EFFECTIVE WEED CONTORL | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-09-24 | — | — | US | disclosed |
| US-4285575-A | USING AN ELECTROCHROMIC ELECTROLYTE CONTAINING A CARBOXYLIC-CONTAINING COMPLEXING AGENT, A FERROUS SALT, A METAL SALT, AND A CHROMOGEN; DURABILITY | CANON KABUSHIKI KAISHA (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4212518-A | ELECTROCHROMIC CELL | CANON KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |
| JP-S54109086-A | IMAGE DISPLAY DEVICE | CANON INC | 1979-08-27 | — | — | JP | disclosed |
| JP-S54107886-A | IMAGE DISPLAY DEVICE | CANON INC | 1979-08-24 | — | — | JP | disclosed |
| US-4153444-A | Herbicidal composition | KUMIAI CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1979-05-08 | — | — | US | disclosed |
| US-4028091-A | BIPYRIDYLIUM SALTS AND A THIOCARBAMATE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |