Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080394 | 0.89 | RAB9A (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4077393 | 0.77 | MAPT (0.57) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL4087581 | 0.76 | AR (0.52) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4077609 | 0.75 | MAPT (0.52) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4076674 | 0.75 | MAPT (0.52) | RAB9ANPC1MEN1KMT2AAR | |
| SCHEMBL3977547 | 0.75 | MEN1 (0.48) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4075018 | 0.75 | SMN1; SMN2 (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4075308 | 0.75 | MEN1 (0.50) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4078198 | 0.73 | AR (0.54) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4077640 | 0.73 | MEN1 (0.38) | RAB9ANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |