SCHEMBL4084860

SCHEMBL4084860

O=P(Oc1c[nH]c2ccc(Br)c(Cl)c12)(Oc1c[nH]c2ccc(Br)c(Cl)c12)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
CYP2A6 P11509 1/20 0.31
CFTR P13569 1/20 0.30
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56849 0.83 CYP2A6 (0.32) CYP2A6NR4A2
SCHEMBL29750724 0.80 CYP2A6 (0.30) CYP2A6NR4A2
SCHEMBL23488 0.80 HTR2A (0.40) CYP2A6NR4A2
SCHEMBL188369 0.80 CYP2A6 (0.30) CYP2A6NR4A2
SCHEMBL29356973 0.80 HTR2A (0.40) CYP2A6NR4A2
Phosphoric Acid SCHEMBL8156858 0.79 HTR2A (0.40) NR4A2
SCHEMBL5058499 0.79 HTR2A (0.40) NR4A2
SCHEMBL31324009 0.79 HTR2A (0.40) NR4A2
SCHEMBL17668115 0.79 HTR2A (0.40) NR4A2
SCHEMBL29008754 0.79 HTR2A (0.40) NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765057-B1 METHOD FOR AGROBACTERIUM TRANSFORMATION FOR DIHAPLOID CORN PLANTS MONSANTO TECHNOLOGY LLC (US) 2015-10-07 EP disclosed
US-7572635-B2 Method for agrobacterium transformation for dihaploid corn plants MONSANTO TECHNOLOGY LLC (US) 2009-08-11 US disclosed
EP-1765057-A1 METHOD FOR AGROBACTERIUM TRANSFORMATION FOR DIHAPLOID CORN PLANTS Monsanto Technology, LLC (US) 2007-03-28 EP disclosed
WO-2006011959-A1 METHOD FOR AGROBACTERIUM TRANSFORMATION FOR DOHAPLOID CORN PLANTS MONSANTO TECHNOLOGY LLC (US) 2006-02-02 WO disclosed
US-20050289673-A1 A Novel Method for Agrobacterium Transformation for Dihaploid Corn Plants MONSANTO TECHNOLOGY LLC (US) 2005-12-29 US disclosed
US-20040210959-A1 A Novel Method for Production of Transformed Dihaploid Corn Plants MONSANTO TECHNOLOGY LLC (US) 2004-10-21 US disclosed