SCHEMBL188369

SCHEMBL188369

O=P([O-])([O-])Oc1c[nH]c2ccc(Br)c(Cl)c12.[Na+].[Na+]

nearest known ligand 0.30

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.30
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750724 1.00 CYP2A6 (0.30) CYP2A6NR4A2
Potassium Ion SCHEMBL415379 0.98
SCHEMBL17668116 0.93 HTR2A (0.37)
SCHEMBL6271251 0.88 MEN1 (0.31)
SCHEMBL56849 0.88 CYP2A6 (0.32) CYP2A6NR4A2
SCHEMBL29206144 0.85
SCHEMBL23488 0.85 HTR2A (0.40) CYP2A6NR4A2
SCHEMBL29356973 0.85 HTR2A (0.40) CYP2A6NR4A2
SCHEMBL5058499 0.84 HTR2A (0.40) NR4A2
SCHEMBL17668115 0.84 HTR2A (0.40) NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117092095-A Combined detection kit for detecting prostate diseases 郑州安图生物工程股份有限公司 2023-11-21 CN claimed
CN-114133551-B Pyrimidine polyether and preparation method and application thereof 万华化学集团股份有限公司 2023-05-30 CN claimed
CN-114133551-A Pyrimidyl polyether and preparation method and application thereof 万华化学集团股份有限公司 2022-03-04 CN claimed
CN-111733069-A Colony counting test piece for fluorescence/visible light double detection of mould and yeast and preparation method thereof 吉林农业大学 2020-10-02 CN claimed
CN-210261792-U Food mould detection and monitoring equipment 福建一品居食品有限公司 2020-04-07 CN claimed
US-9090929-B2 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LIMITED (GB) 2015-07-28 US claimed
EP-2186906-B1 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LTD (GB) 2012-07-25 EP claimed
EP-1725676-B1 MEASURING CONTAMINATION MYCOMETER AS (DK) 2012-04-25 EP claimed
US-20110244510-A1 Filtration method for detecting microbial contamination MYCOMETER A/S (DK) 2011-10-06 US claimed
US-7939285-B2 Filtration method for detecting microbial contamination MYCOMETER APS (DK) 2011-05-10 US claimed
EP-2186906-A2 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LIMITED (GB) 2010-05-19 EP claimed
US-20100120086-A1 MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI OXOID LTD. (GB) 2010-05-13 US claimed
US-20070178446-A1 Measuring contamination MYCOMETER A/S (DK) 2007-08-02 US claimed
EP-1725676-A1 MEASURING CONTAMINATION Mycometer ApS (DK) 2006-11-29 EP claimed
WO-2005083109-A1 MEASURING CONTAMINATION MYCOMETER APS (DK) 2005-09-09 WO claimed
EP-0476930-B1 Enzyme assays SANKYO CO (JP) 1997-11-12 EP claimed
EP-0476930-A1 Enzyme assays Sankyo Company Limited (JP) 1992-03-25 EP claimed
US-20250258173-A1 METHODS AND REAGENTS OF IMMUNOLOGICALLY DETECTING SARS-CoV-2 FUJIREBIO INC. (JP) 2025-08-14 US disclosed
WO-1991018019-A1 SOLUBLE SINGLE CHAIN T CELL RECEPTORS E.R. SQUIBB & SONS, INC. (US) 1991-11-28 WO disclosed
EP-0398703-A1 Device containing a microbiological dry culture medium MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-22 EP disclosed