SCHEMBL4085510

SCHEMBL4085510

O=c1ccn([C@@H]2O[C@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.62
SLC28A2 O43868 1/20 0.62
SLC29A1 Q99808 1/20 0.62
SLC28A3 Q9HAS3 1/20 0.62
P2RY6 Q15077 9/20 0.61
P2RY2 P41231 12/20 0.60
P2RY4 P51582 4/20 0.60
P2RY14 Q15391 5/20 0.59
TYMP P19971 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332109 1.00 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL918582 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL12513082 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL918583 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1317089 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL12434636 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL26502752 0.92 TYMP (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3316264 0.91 P2RY14 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5671913 0.90 P2RY6 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL7922849 0.90 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120053443-A Application of 5' -O-trityl uridine and derivatives thereof in preparation of medicines for treating cerebral infarction 中国中医科学院中医药健康产业研究所 2025-05-30 CN claimed
EP-0682670-B1 DEOXYGENATION OF CIS VICINAL DIOLS RAYLO CHEMICALS INC (CA) 1998-05-06 EP claimed
US-5410033-A Deoxygenation of cis vicinal diols to make didehydro dideoxy nucleosidies and synthetic intermediates TEROCHEM LABORATORIES LIMITED (CA) 1995-04-25 US claimed
CN-120053443-A Application of 5' -O-trityl uridine and derivatives thereof in preparation of medicines for treating cerebral infarction 中国中医科学院中医药健康产业研究所 2025-05-30 CN disclosed
CN-120053443-A Application of 5' -O-trityl uridine and derivatives thereof in preparation of medicines for treating cerebral infarction 中国中医科学院中医药健康产业研究所 2025-05-30 CN disclosed
CN-120053443-A Application of 5' -O-trityl uridine and derivatives thereof in preparation of medicines for treating cerebral infarction 中国中医科学院中医药健康产业研究所 2025-05-30 CN disclosed
US-7507859-B2 Functional synthetic molecules and macromolecules for gene delivery FIFTH BASE LLC (US) 2009-03-24 US disclosed
EP-1644479-A4 FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY GRINSTAFF MARK W (US) 2008-04-23 EP disclosed
US-20060241071-A1 Functional synthetic molecules and macromolecules for gene delivery FIFTH BASE LLC 2006-10-26 US disclosed
EP-1644479-A2 FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY Grinstaff, Mark, W. (US) 2006-04-12 EP disclosed
WO-2005007810-A2 FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY GRINSTAFF MARK W (US) 2005-01-27 WO disclosed
EP-0682670-B1 DEOXYGENATION OF CIS VICINAL DIOLS RAYLO CHEMICALS INC (CA) 1998-05-06 EP disclosed
US-5410033-A Deoxygenation of cis vicinal diols to make didehydro dideoxy nucleosidies and synthetic intermediates TEROCHEM LABORATORIES LIMITED (CA) 1995-04-25 US disclosed
US-5212294-A Production of 2',3'-dideoxy-2',3'-didehydronucleosides BRISTOL-MYERS SQUIBB COMPANY (US) 1993-05-18 US disclosed
US-5130421-A Production of 2',3'-dideoxy-2',3'-didehydronucleosides BRISTOL-MYERS COMPANY (US) 1992-07-14 US disclosed
US-4904770-A Production of 2',3'-dideoxy-2',3'-didehydronucleosides BRISTOL-MYERS COMPANY (US) 1990-02-27 US disclosed
EP-0334368-A2 Production of 2',3'-dideoxy-2',3'-Didehydronucleosides Bristol-Myers Squibb Company (US) 1989-09-27 EP disclosed
EP-0316017-A2 2',3'-Dideoxy-2'-fluoronucleosides Bristol-Myers Squibb Company (US) 1989-05-17 EP disclosed
EP-0082668-A1 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections BEECHAM GROUP PLC (GB) 1983-06-29 EP disclosed
EP-0061283-A1 Antiviral agents, their preparation and use BEECHAM GROUP PLC (GB) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241071-A1 Functional synthetic molecules and macromolecules for gene delivery ANXA6, STING1, POLRMT SLC28A1 1592/4885SLC28A2 1890/4885SLC29A1 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.