Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436579 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL2436577 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7967595 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7967589 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7970902 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7970893 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7966546 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7973450 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7966543 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7966530 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | KDM4E 2132/4885ALDH1A1 56/4885HPGD 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.