Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967595 | 1.00 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL81317 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL29636389 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL81318 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL8937324 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL8937327 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL8937421 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7429374 | 0.86 | FDPS (0.63) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL4085532 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL27858762 | 0.85 | KDM4E (0.97) | KDM4EALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |