Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873896 | 0.74 | ALDH1A1 (0.46) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL1229735 | 0.74 | CES1 (0.42) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL6826582 | 0.72 | MAPK1 (0.43) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL4080316 | 0.72 | MAPK1 (0.43) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL9698748 | 0.71 | CES1 (0.44) | CES1KCNN4MAPK1ALDH1A1ALOX15 | |
| SCHEMBL4080546 | 0.71 | KCNN4 (0.44) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL20752423 | 0.70 | MAPK1 (0.44) | CES1KCNN4MAPK1ALDH1A1ALOX15 | |
| SCHEMBL17420765 | 0.70 | MAPK1 (0.44) | CES1KCNN4MAPK1ALDH1A1ALOX15 | |
| SCHEMBL11122765 | 0.68 | CES1 (0.41) | CES1KCNN4MAPK1LMNAALDH1A1 | |
| SCHEMBL5161276 | 0.68 | ALDH1A1 (0.38) | CES1KCNN4MAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | claimed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | claimed |
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |
| WO-2007134127-A3 | AGENTS FOR IMAGING APOPTOSIS | UNIV TEXAS (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | disclosed |