Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384303 | 0.79 | CES1 (0.40) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL27267147 | 0.76 | KCNN4 (0.33) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL7873896 | 0.74 | ALDH1A1 (0.46) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL1229735 | 0.74 | CES1 (0.42) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL4080316 | 0.72 | MAPK1 (0.43) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL6826582 | 0.72 | MAPK1 (0.43) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL4429025 | 0.71 | MAPT (0.45) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL4080546 | 0.71 | KCNN4 (0.44) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL4085558 | 0.71 | CES1 (0.40) | CES1KCNN4ALDH1A1ALOX15HDAC3 | |
| SCHEMBL4372562 | 0.70 | CES1 (0.47) | CES1KCNN4ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482594-A1 | Tylosin derivative and method for preparing the same | MERCIAN CORPORATION (JP) | 1992-04-29 | — | — | EP | disclosed |