Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CNR2 | P34972 | 10/20 | 0.61 |
| ▸ | CNR1 | P21554 | 6/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086799 | 0.80 | PTPN1 (0.63) | ALDH1A1KMT2ANOD1GAAPOLB | |
| SCHEMBL3761447 | 0.79 | ABCC1 (0.55) | ALDH1A1TSHRCNR2CNR1KMT2A | |
| SCHEMBL4132193 | 0.79 | ALDH1A1 (0.73) | ALDH1A1TSHRCNR2CNR1KIF11 | |
| SCHEMBL4086082 | 0.78 | CNR2 (0.84) | ALDH1A1TSHRCNR2CNR1KIF11 | |
| SCHEMBL12218514 | 0.78 | CNR2 (0.82) | ALDH1A1TSHRCNR2CNR1KIF11 | |
| SCHEMBL4091575 | 0.78 | CNR2 (0.62) | ALDH1A1TSHRCNR2CNR1KIF11 | |
| SCHEMBL4094737 | 0.77 | ATM (0.55) | ALDH1A1TSHRCNR2CNR1KMT2A | |
| SCHEMBL4091622 | 0.77 | PTPN1 (0.63) | ALDH1A1KMT2AGAAPOLBKDM4E | |
| SCHEMBL14156265 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRCNR2CNR1KIF11 | |
| SCHEMBL21603653 | 0.76 | FLT3 (0.68) | ALDH1A1TSHRCNR2CNR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | ALDH1A1 1504/4885TSHR 463/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.