SCHEMBL4085660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4093480	0.87	NTRK1 (0.42)	CA12CA1CA2CA6CA7
	SCHEMBL4098596	0.86	CXCR2 (0.41)	CA12CA1CA2CA6CA7
	SCHEMBL4093400	0.85	HSP90AA1 (0.46)	CA12CA1CA2CA6CA7
	SCHEMBL4086244	0.83	TP53 (0.48)	RXFP1HSP90AA1NPC1RAB9ASMN1; SMN2
	SCHEMBL14563047	0.81	CA1 (0.53)	CA12CA1CA2CA6CA7
	SCHEMBL4092198	0.81	SLC6A12 (0.43)	CA12CA1CA2CA6CA7
	SCHEMBL4087263	0.80	NTRK1 (0.39)	CA12CA1CA2CA6CA7
	SCHEMBL2847985	0.78	HSP90AA1 (0.50)	CXCR2HSP90AA1NPC1RAB9ASMN1; SMN2
	SCHEMBL4096516	0.77	HRH4 (0.43)	HSP90AA1NPC1RAB9ASMN1; SMN2PAK4
	SCHEMBL4093130	0.77	HTT (0.50)	CA12CA1CA2CA6CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.