SCHEMBL4086244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4093400	0.88	HSP90AA1 (0.46)	HSP90AA1ALDH1A1TDP1SMN1; SMN2NPC1
	SCHEMBL4091801	0.85	TP53 (0.52)	TP53HSP90AA1PKML3MBTL1ALDH1A1
	SCHEMBL4085660	0.83	CA12 (0.49)	HSP90AA1SMN1; SMN2NPC1RAB9ARXFP1
	SCHEMBL4098596	0.83	CXCR2 (0.41)	HSP90AA1SMN1; SMN2NPC1RAB9ARXFP1
	SCHEMBL4096516	0.81	HRH4 (0.43)	TP53HSP90AA1L3MBTL1SMN1; SMN2NPC1
	SCHEMBL2847985	0.81	HSP90AA1 (0.50)	HSP90AA1TDP1SMN1; SMN2NPC1RAB9A
	SCHEMBL4093480	0.81	NTRK1 (0.42)	HSP90AA1SMN1; SMN2NPC1RAB9ARXFP1
	SCHEMBL4092198	0.80	SLC6A12 (0.43)	ALDH1A1HPGD
	SCHEMBL4093130	0.79	HTT (0.50)	HSP90AA1PKMALDH1A1SMN1; SMN2TSHR
	SCHEMBL4092055	0.77	HSP90AA1 (0.46)	HSP90AA1L3MBTL1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.