Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085506 | 0.87 | GAA (0.57) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4092146 | 0.85 | HSD17B1 (0.59) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4093081 | 0.83 | HSD17B1 (0.59) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL16610098 | 0.82 | MAPT (0.84) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL2433131 | 0.76 | MAPT (0.75) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL16353842 | 0.76 | CYP3A4 (0.76) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL13271684 | 0.76 | CYP3A4 (0.80) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4096345 | 0.76 | HSD17B1 (0.62) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL8234001 | 0.75 | CYP3A4 (0.81) | MAPTGAACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19632801 | 0.74 | MAPT (0.81) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | MAPT 929/4885GAA 316/4885CYP3A4 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.