⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548982 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL5548980 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL10912039 | 0.80 | — | — | |
| SCHEMBL4445301 | 0.79 | — | — | |
| SCHEMBL9603875 | 0.79 | — | — | |
| SCHEMBL27755489 | 0.78 | — | — | |
| SCHEMBL17598252 | 0.77 | — | — | |
| SCHEMBL8504067 | 0.77 | — | — | |
| SCHEMBL400163 | 0.77 | — | — | |
| SCHEMBL308302 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214066-B1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL FLUOROFORMATES | SOLVAY FLUOR GMBH (DE) | 2024-02-21 | — | — | EP | claimed |
| EP-3214066-A2 | PROCESS FOR THE PREPARATION OF FLUOROALKYL FLUOROFORMATES | Solvay Fluor GmbH (DE) | 2017-09-06 | — | — | EP | claimed |
| WO-2013026777-A1 | FLUOROALKYL S-(FLUORO)ALKYL THIOCARBONATES, A METHOD FOR THE PREPARATION OF FLUOROALKYL S-(FLUORO)ALKYL THIOCARBONATES, AND THEIR USE | SOLVAY SA (BE) | 2013-02-28 | — | — | WO | claimed |
| EP-2454226-A1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL (FLUORO)ALKYL CARBONATES AND CARBAMATES | Solvay Fluor GmbH (DE) | 2012-05-23 | — | — | EP | claimed |
| US-20120116111-A1 | Process for the preparation of fluoroalkyl (fluoro)alkyl carbonates and carbamates | SOLVAY FLUOR GMBH (DE) | 2012-05-10 | — | — | US | claimed |
| WO-2011006822-A1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL (FLUORO)ALKYL CARBONATES AND CARBAMATES | SOLVAY FLUOR GMBH (DE) | 2011-01-20 | — | — | WO | claimed |
| EP-1730132-A2 | PROCESS FOR PREPARING PHARMACEUTICALLY ACCEPTABLE SALTS OF DULOXETINE AND INTERMEDIATES THEREOF | Teva Pharmaceutical Industries Ltd (IL) | 2006-12-13 | — | — | EP | claimed |
| US-20060194869-A1 | Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2006-08-31 | — | — | US | claimed |
| WO-2006071868-A2 | PROCESS FOR PREPARING PHARMACEUTICALLY ACCEPTABLE SALTS OF DULOXETINE AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-07-06 | — | — | WO | claimed |
| US-5091581-A | Reacting diaminonitrobenzene with chloroalkyl chloroformate | HANS SCHWARZKOPF GMBH (DE) | 1992-02-25 | — | — | US | claimed |
| JP-3017045-A | — | — | None | — | — | JP | disclosed |
| JP-7149696-A | — | — | None | — | — | JP | disclosed |
| CN-114728883-B | Ibuprofen ester prodrug, pharmaceutical composition, preparation method and application | 南京海融医药科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | SEAPORT THERAPEUTICS, INC. | 2024-06-27 | — | — | US | disclosed |
| CN-118063537-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-05-24 | — | — | CN | disclosed |
| JP-H07149696-A | PREPARATION OF HYDROXYALKYLAMINONITROBENZENE DERIVATIVE | CASSELLA AG | 1995-06-13 | — | — | JP | disclosed |
| US-5414128-A | Dehydrofluorination for amination | CASSELLA AG (DE) | 1995-05-09 | — | — | US | disclosed |
| US-5091581-A | Reacting diaminonitrobenzene with chloroalkyl chloroformate | HANS SCHWARZKOPF GMBH (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5091581-A | Reacting diaminonitrobenzene with chloroalkyl chloroformate | HANS SCHWARZKOPF GMBH (DE) | 1992-02-25 | — | — | US | disclosed |
| JP-H0317045-A | SELECTIVE PREPARATION OF N4-SUBSTITUTED 1,4-DIAMINO-2-NIROBENZENE AND N4-SUBSTITUTED 1,4-DIAMINO-2-NITROBENZENE | HANS SCHWARZKOPF GMBH | 1991-01-25 | — | — | JP | disclosed |