SCHEMBL8504067

SCHEMBL8504067

C/C=C/COC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3350706 1.00
SCHEMBL5548980 0.84 ALDH1A1 (0.36)
SCHEMBL5548982 0.84 ALDH1A1 (0.36)
SCHEMBL7612173 0.82 SOAT1 (0.34)
SCHEMBL27525255 0.79 FAAH (0.31)
SCHEMBL10595745 0.79 ALDH1A1 (0.41)
SCHEMBL1598833 0.79 ALDH1A1 (0.41)
SCHEMBL14883634 0.78
SCHEMBL469873 0.77
SCHEMBL5697682 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170073324-A1 Bifidenone Compositions and Methods of Use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-03-16 US disclosed
US-9562031-B1 Phenethyldihydrobenzodioxolones and methods of use SEQUOIA SCIENCES, INC. (US) 2017-02-07 US disclosed
EP-0879224-A4 NOVEL POLY(MONOPEROXYCARBONATES) ATOCHEM NORTH AMERICA ELF (US) 1999-05-26 EP disclosed
EP-0879224-A1 NOVEL POLY(MONOPEROXYCARBONATES) ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-25 EP disclosed
WO-1998007684-A1 NOVEL POLY(MONOPEROXYCARBONATES) ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-02-26 WO disclosed
WO-1991000301-A1 (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES AKZO N.V. (NL) 1991-01-10 WO disclosed
US-4376731-A 2-NITRILES THEREOF BOEHRINGER MANNHEIM GMBH (DE) 1983-03-15 US disclosed