SCHEMBL4086040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4094051	0.82	HSP90AB1 (0.47)	HSP90AA1RAB9ACYP2C19
	SCHEMBL4091505	0.76	HSP90AA1 (0.61)	HSP90AA1ADORA2AADORA1LMNAL3MBTL1
	SCHEMBL4086273	0.69	HSP90AA1 (1.00)	HSP90AA1
	SCHEMBL17349607	0.67	HSP90AA1 (0.47)	HSP90AA1SMN1; SMN2ALDH1A1
	SCHEMBL4096157	0.67	HSP90AB1 (0.46)	HSP90AA1LMNAL3MBTL1
	SCHEMBL4086622	0.66	HSP90AA1 (0.48)	HSP90AA1L3MBTL1
	SCHEMBL4091826	0.66	HSP90AA1 (0.46)	HSP90AA1L3MBTL1ALDH1A1
	SCHEMBL4096191	0.66	HSP90AB1 (0.43)	HSP90AA1SMN1; SMN2L3MBTL1ALDH1A1CYP2C19
	SCHEMBL4085660	0.65	CA12 (0.49)	HSP90AA1NPC1RAB9ASMN1; SMN2LMNA
	SCHEMBL4086244	0.65	TP53 (0.48)	HSP90AA1ADORA2AADORA1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.