SCHEMBL4086253

SCHEMBL4086253

FC(F)(F)c1cccc([C](c2cccc(C(F)(F)F)c2)c2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.69
SRD5A2 P31213 1/20 0.56
LMNA P02545 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
P2RX1 P51575 1/20 0.53
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
MGLL Q99685 1/20 0.52
POLB P06746 2/20 0.51
HPGD P15428 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MAOB P27338 1/20 0.50
MAPT P10636 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KCNK3 O14649 1/20 0.50
PTGS1 P23219 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350153 0.85 CES2 (0.74) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL10842400 0.84 CES2 (0.67) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL543288 0.84 CES2 (0.67) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL7447900 0.82 CES2 (0.64) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL8865659 0.82 CES2 (0.64) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL17134217 0.82 CES2 (0.64) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL3176325 0.82 CES2 (1.00) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL1237189 0.82 SRD5A2 (0.79) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL3554040 0.80 CES2 (0.62) CES2SRD5A2LMNANPSR1P2RX1
SCHEMBL10672352 0.80 CES2 (0.62) CES2SRD5A2LMNANPSR1P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed