Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CCR9 | P51686 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 8/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097166 | 0.90 | CCR9 (0.45) | TP53MAPTTHRBCCR9CCR2 | |
| SCHEMBL4092463 | 0.88 | CCR2 (0.55) | TP53MAPTTHRBCCR9CCR2 | |
| SCHEMBL4093856 | 0.81 | CCR2 (0.38) | TP53MAPTTHRBCCR9CCR2 | |
| SCHEMBL4093522 | 0.77 | CCR2 (0.53) | MAPTTHRBCCR9CCR2ABCB11 | |
| SCHEMBL4093410 | 0.76 | TP53 (0.44) | TP53MAPTTHRBCCR2ALDH1A1 | |
| SCHEMBL4092145 | 0.74 | MAPT (0.42) | TP53MAPTTHRBCCR9CCR2 | |
| SCHEMBL4104997 | 0.74 | CCR2 (0.53) | TP53MAPTTHRBCCR9CCR2 | |
| SCHEMBL7682483 | 0.72 | CCR2 (0.58) | CCR2ABCB11 | |
| SCHEMBL4093394 | 0.72 | CCR2 (0.55) | CCR9CCR2 | |
| SCHEMBL4097147 | 0.71 | CCR2 (0.52) | CCR9CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | TP53 1258/4885MAPT 54/4885THRB 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.