Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382234 | 0.83 | GPR84 (0.58) | GPR84IDO1LMNATUBB4ATUBB | |
| SCHEMBL8268363 | 0.83 | GPR84 (0.58) | GPR84IDO1LMNATUBB4ATUBB | |
| Ethoxycarbonyl Group SCHEMBL27412906 | 0.82 | GPR84 (0.45) | GPR84IDO1LMNAF7F3 | |
| SCHEMBL38663621 | 0.78 | GPR84 (0.62) | GPR84IDO1F7F3TUBB4A | |
| SCHEMBL29777537 | 0.78 | ATM (0.56) | IDO1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL12376 | 0.78 | ATM (0.56) | IDO1LMNATUBB4ATUBBTUBA3C | |
| Ammonia Solution, Strong SCHEMBL23704299 | 0.77 | ATM (0.54) | IDO1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL27449488 | 0.76 | GPR84 (0.55) | GPR84IDO1F7F3TUBB4A | |
| SCHEMBL3180061 | 0.76 | F7 (0.56) | GPR84IDO1F7F3TUBB4A | |
| SCHEMBL17621798 | 0.76 | MAP3K14 (0.51) | GPR84IDO1F7F3TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| CN-117402100-A | Preparation method of 3,3' -diindolylmethane and derivatives thereof participated by carbon dioxide | 山西大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-115073427-B | Indole biazaheterocyclic compound and synthesis method and application thereof | 兰州大学 | 2023-10-10 | — | — | CN | disclosed |
| WO-2023002246-A1 | NOVEL 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2023-01-26 | — | — | WO | disclosed |
| CN-109232362-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-115073427-A | Indole-linked nitrogen heterocyclic compound and synthesis method and application thereof | 兰州大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-114031541-B | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-08-19 | — | — | CN | disclosed |
| US-20220168280-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. | 2022-06-02 | — | — | US | disclosed |
| CN-114031541-A | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-02-11 | — | — | CN | disclosed |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| WO-2003014116-A1 | PYRROLO[2.1-A]ISOQUINOLINE DERIVATIVES | BAYER CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
| EP-0107618-B1 | N-SUBSTITUTED-2-(1-IMIDAZOLYL)-INDOLES | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | disclosed |
| US-4539410-A | THROMBOXANE SYNEHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0107618-A1 | N-substituted-2-(1-imidazolyl)-indoles | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4101583-A | Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4080341-A | Carbazolenine and indole compounds | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067875-A | Certain N-phenyl or N-pyridyl aza sulfonium salts | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3992392-A | Synthesis of indoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168280-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | KRAS, NRAS, HRAS | GPR84 1877/4885IDO1 4527/4885LMNA 2823/4885 |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | EZH2, EZH1, BMI1 | GPR84 4431/4885IDO1 2820/4885LMNA 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.