Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180061 | 0.77 | F7 (0.56) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL4086846 | 0.76 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL17982265 | 0.76 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL38663621 | 0.75 | GPR84 (0.62) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL12464834 | 0.73 | HTR2A (0.71) | GPR84HTR2ATRPM8SLC6A4IDO1 | |
| SCHEMBL3780100 | 0.72 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL17439076 | 0.72 | F7 (0.59) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL28077797 | 0.72 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL30415771 | 0.72 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL208040 | 0.72 | GPR84 (0.58) | GPR84HTR2ATRPM8F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | GPR84 4777/4885HTR2A 3605/4885TRPM8 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.