Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075045 | 0.85 | MAPT (0.65) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4086849 | 0.80 | SMN1; SMN2 (0.60) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4408570 | 0.79 | GAA (0.61) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4487938 | 0.79 | GAA (0.61) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL7930002 | 0.78 | GAA (0.60) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL10921733 | 0.76 | KMT2A (0.68) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL21484734 | 0.75 | ABL1 (0.69) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL12527532 | 0.73 | ABL1 (0.74) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL23704807 | 0.73 | LMNA (0.54) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL28673842 | 0.72 | MEN1 (0.62) | MAPTKMT2ASMN1; SMN2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |