Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771939 | 0.93 | GAA (0.59) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL2901212 | 0.80 | GAA (0.71) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL4094277 | 0.79 | GAA (0.65) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL9158980 | 0.79 | GAA (0.56) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL9150456 | 0.78 | GAA (0.48) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL1647940 | 0.77 | GAA (0.67) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL10079252 | 0.77 | GAA (0.58) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL28800695 | 0.77 | GAA (0.58) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL29494819 | 0.77 | GAA (0.58) | GAAHTTPOLBKMT2ARECQL | |
| SCHEMBL9682135 | 0.77 | GAA (0.58) | GAAHTTPOLBKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118400-A1 | RESIN COMPOSITION | ZEON CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |