Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477965 | 0.92 | ALDH1A1 (0.51) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| SCHEMBL1108340 | 0.92 | ALDH1A1 (0.51) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| SCHEMBL5916451 | 0.92 | ALDH1A1 (0.51) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7385556 | 0.91 | ALDH1A1 (0.53) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7387839 | 0.91 | ALDH1A1 (0.53) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3871196 | 0.91 | ALDH1A1 (0.53) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| SCHEMBL7273637 | 0.88 | ESR1 (0.55) | PTGS2ALDH1A1LTA4HESR1ESR2 | |
| SCHEMBL29183302 | 0.88 | ACACB (0.53) | PTGS2LTA4HTPH1ACACBPPARG | |
| SCHEMBL2292317 | 0.88 | ACACB (0.53) | PTGS2LTA4HTPH1ACACBPPARG | |
| SCHEMBL8255298 | 0.88 | ACACB (0.53) | PTGS2LTA4HTPH1ACACBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-03-26 | — | — | US | disclosed |
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |
| EP-1883629-A2 | NOVEL HETEROCYCLIC DERIVATIVES | Orchid Research Laboratories Limited (IN) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006123229-A2 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | CYP3A5, CYP3A7, UGT2B7 | PTGS2 954/4885ALDH1A1 281/4885LTA4H 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.