Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800278 | 0.88 | SLC22A6 (0.47) | SLC22A6STING1NPC1RAB9AMEN1 | |
| SCHEMBL30903953 | 0.88 | SLC22A6 (0.47) | SLC22A6STING1NPC1RAB9AMEN1 | |
| SCHEMBL458847 | 0.88 | SLC22A6 (0.47) | SLC22A6STING1NPC1RAB9AMEN1 | |
| SCHEMBL3279763 | 0.87 | SLC22A6 (0.50) | SLC22A6NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28311486 | 0.81 | STING1 (0.39) | STING1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9299192 | 0.74 | NR4A2 (0.42) | ALDH1A1POLB | |
| SCHEMBL28034562 | 0.74 | SLC22A6 (0.50) | SLC22A6NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL27808262 | 0.73 | SLC22A6 (0.57) | SLC22A6NPC1MEN1KMT2AMAPT | |
| SCHEMBL540158 | 0.73 | SLC22A6 (0.56) | SLC22A6KDM4EALDH1A1HPGDPBRM1 | |
| SCHEMBL31034497 | 0.73 | SLC22A6 (0.56) | SLC22A6KDM4EALDH1A1HPGDPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075876-A1 | Altered insulin-like growth factor binding proteins | THE UNIVERSITY OF ADELAIDE | 2009-03-19 | — | — | US | disclosed |
| US-7488798-B2 | Altered insulin-like growth factor binding proteins | UNIVERSITY OF ADELAIDE (AU) | 2009-02-10 | — | — | US | disclosed |
| US-20060153853-A1 | Altered insulin-like grwoth factor binding proteins | THE UNIVERSITY OF ADELAIDE (AU) | 2006-07-13 | — | — | US | disclosed |