SCHEMBL9299192

SCHEMBL9299192

Cc1ccc(N)cc1.O=P(O)(O)Oc1c[nH]c2cc(Cl)ccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.42
GPR84 Q9NQS5 1/20 0.37
POLB P06746 1/20 0.36
DUSP3 P51452 1/20 0.36
PTPN5 P54829 1/20 0.36
PTPN11 Q06124 1/20 0.36
DYRK1A Q13627 2/20 0.35
PYGL P06737 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTR2A P28223 2/20 0.34
IDO1 P14902 2/20 0.34
PRKAB2 O43741 1/20 0.34
PRKAG1 P54619 1/20 0.34
PRKAA2 P54646 1/20 0.34
PRKAA1 Q13131 1/20 0.34
PRKAG3 Q9UGI9 1/20 0.34
PRKAG2 Q9UGJ0 1/20 0.34
PRKAB1 Q9Y478 1/20 0.34
GSK3B P49841 1/20 0.34
SNCA P37840 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305772 0.87 NR4A2 (0.49) NR4A2GPR84DYRK1APYGLALDH1A1
O-Tolylamine SCHEMBL30712038 0.84 NR4A2 (0.41) NR4A2GPR84DYRK1APYGLHTR2A
SCHEMBL30712037 0.83 PRKAB2 (0.37) NR4A2HTR2APRKAB2PRKAG1PRKAA2
SCHEMBL2124028 0.83 PRKAB2 (0.37) NR4A2HTR2APRKAB2PRKAG1PRKAA2
SCHEMBL458847 0.83 SLC22A6 (0.47) POLBALDH1A1HTR2A
SCHEMBL7800278 0.83 SLC22A6 (0.47) POLBALDH1A1HTR2A
SCHEMBL30903953 0.83 SLC22A6 (0.47) POLBALDH1A1HTR2A
SCHEMBL27960056 0.76 F7 (0.51) NR4A2GPR84PYGLHTR2AIDO1
SCHEMBL305771 0.76 GPR84 (0.49) NR4A2GPR84DYRK1APYGLALDH1A1
SCHEMBL3739490 0.75 HTR2A (0.36) ALDH1A1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5364767-A 6-chloroindole derivatives; colorimetric and quantitative analysis RESEARCH ORGANICS, IN. (US) 1994-11-15 US claimed
US-5364767-A 6-chloroindole derivatives; colorimetric and quantitative analysis RESEARCH ORGANICS, IN. (US) 1994-11-15 US disclosed