Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088184 | 1.00 | CPA3 (0.42) | CPA3FOLH1CRHBPCRHR2CPA1 | |
| SCHEMBL594166 | 0.86 | CRHBP (0.43) | CRHBPCRHR2CPA1CES2CES1 | |
| SCHEMBL594167 | 0.86 | CRHBP (0.43) | CRHBPCRHR2CPA1CES2CES1 | |
| SCHEMBL20856984 | 0.80 | FNTA (0.47) | CRHBPCRHR2CPA1 | |
| SCHEMBL16599212 | 0.79 | EPOR (0.47) | CRHBPCRHR2CPA1 | |
| SCHEMBL16599213 | 0.79 | EPOR (0.47) | CRHBPCRHR2CPA1 | |
| SCHEMBL20522200 | 0.77 | KDM6B (0.47) | CRHBPCRHR2CPA1 | |
| SCHEMBL20522201 | 0.77 | KDM6B (0.47) | CRHBPCRHR2CPA1 | |
| SCHEMBL27004369 | 0.77 | FOLH1 (0.50) | CPA3FOLH1CA12CA9CTRB1 | |
| SCHEMBL27004114 | 0.77 | FOLH1 (0.50) | CPA3FOLH1CA12CA9CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797177-A4 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2008-07-09 | — | — | EP | claimed |
| EP-1797177-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | The Scripps Research Institute (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006034410-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | THE SCRIPPS RESARCH INSTITUTE (US) | 2006-03-30 | — | — | WO | claimed |
| EP-4371116-A2 | METHODS FOR OPTIMISING PROTEIN PRODUCTION | United Kingdom Research and Innovation (GB) | 2024-05-22 | — | — | EP | disclosed |
| EP-4347799-A1 | MICROORGANISMS AND USES THEREOF | United Kingdom Research and Innovation (GB) | 2024-04-10 | — | — | EP | disclosed |
| WO-2023285596-A2 | METHODS FOR OPTIMISING PROTEIN PRODUCTION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-01-19 | — | — | WO | disclosed |
| WO-2021127547-A2 | MONOCLONAL ANTIBODY FUSIONS | QUIDEL CORPORATION (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021072167-A1 | COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2019006260-A1 | METHODS OF MAKING PROTEINS WITH NON-STANDARD AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018151829-A1 | FUNCTIONALIZED ERYTHROID CELLS | RUBIUS THERAPEUTICS, INC. (US) | 2018-08-23 | — | — | WO | disclosed |
| WO-2015048364-A1 | RECOMBINANT CELLS AND ORGANISMS HAVING PERSISTENT NONSTANDARD AMINO ACID DEPENDENCE AND METHODS OF MAKING THEM | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-02 | — | — | WO | disclosed |
| EP-2069481-A2 | GENETIC INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN MAMMALIAN CELLS | The Scripps Research Institute (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1797177-A4 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008073184-A2 | GENETIC INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN MAMMALIAN CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-06-19 | — | — | WO | disclosed |
| EP-1807515-A4 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | SCRIPPS RESEARCH INST (US) | 2008-06-18 | — | — | EP | disclosed |
| EP-1807515-A2 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | The Scripps Research Institute (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1797177-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | The Scripps Research Institute (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006110182-A2 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-2006034410-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | THE SCRIPPS RESARCH INSTITUTE (US) | 2006-03-30 | — | — | WO | disclosed |